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Ionis Pharmaceuticals, Inc.(IONS)

Description: Ionis Pharmaceuticals, Inc., a RNA-targeted drug discovery and development company, focuses on developing drugs for patients with severe and rare diseases. It markets KYNAMRO for the treatment of homozygous familial hypercholesterolemia. The company's drugs in Phase III development include volanesorsen for the treatment of patients with familial chylomicronemia syndrome and familial partial lipodystrophy; IONIS-TTRRx, a drug for the treatment of patients with various forms of TTR amyloidosis, including familial amyloid polyneuropathy, familial amyloid cardiomyopathy, and wild-type TTR amyloidosis; and nusinersen, a drug for the treatment of infants and children with spinal muscular atrophy. It is also developing Custirsen, which is in two Phase III studies to treat cancer; and Plazomicin that is Phase III study for the treatment of severe bacterial infection. In addition, the company is developing products, which are Phase II clinical trials include IONIS-DMPK-2.5Rx for myotonic dystrophy type 1; IONIS-HTTR for huntington's disease; ATL1103 for acromegaly; IONIS-FXIRx (BAY 2306001) for clotting disorders; IONIS-APO(a)-LRx for high Lp; IONIS-ANGPTL3-LRx for mixed dyslipidemias; Apatorsen (OGX-427) and IONIS-STAT3-2.5Rx (AZD9150) for cancers; EXC 001 (PF-06473871) for scarring; ATL1102 for multiple sclerosis; and RG-101 for hepatitis C virus infection, as well as products for the treatment of diabetes and obesity. Further, its products in Phase I clinical include IONIS-GCCRRx for cushing's syndrome; IONIS-PKKRx for hereditary angioedema; RG-012 for alport syndrome; IONIS-AR-2.5Rx (AZD5312) for prostate cancer; IONIS-HBVRx for hepatitis B virus infection; IONIS-GSK4-LRx for ocular disease; and IONIS-DGAT2Rx for nonalcoholic steatohepatitis. The company was formerly known as Isis Pharmaceuticals, Inc. and changed its name to Ionis Pharmaceuticals, Inc. in December 2015. Ionis Pharmaceuticals, Inc. was founded in 1989 and is headquartered in Carlsbad, California.


Keywords: Cancer Diabetes Organ Systems Drug Discovery Prostate Cancer Rare Diseases Alcohol Disorders Multiple Sclerosis Obesity Hepatitis B Neurological Disorders Genetics Lipid Cholesterol Orphan Drug Hepatitis C Dystrophy Steatohepatitis Amyloidosis Hypercholesterolemia Huntington's Disease Treatment Of Diabetes Hereditary Angioedema Amyloid Angioedema Hepatitis C Virus Dyslipidemia Hepatitis B Virus Therapeutic Gene Modulation Acromegaly Cardiomyopathy Spinal Muscular Atrophy Myopathy Myotonic Dystrophy Polyneuropathy Lipodystrophy Alport Syndrome Antisense RNA Ocular Disease Severe And Rare Diseases Familial Chylomicronemia Syndrome Hepatitis C Virus Infection Homozygous Familial Hypercholesterolemia Mozy TTR Amyloidosis Apatorsen Cushing's Syndrome Familial Amyloid Polyneuropathy Familial Partial Lipodystrophy Ionis Mixed Dyslipidemia Onemia

Home Page: www.ionispharma.com

IONS Technical Analysis

2855 Gazelle Court
Carlsbad, CA 92010
United States
Phone: 760 931 9200


Officers

Name Title
Dr. Brett P. Monia Ph.D. Founder, CEO & Director
Ms. Elizabeth L. Hougen Exec. VP of Fin. & CFO
Ms. Onaiza Cadoret-Manier Exec. VP, Chief Global Product Strategy & Operations Officer
Mr. Patrick R. O'Neil Esq. Exec. VP, Chief Legal Officer, Gen. Counsel & Corp. Sec.
Dr. Stanley T. Crooke Scientific Advisor
Ms. B. Lynne Parshall Esq., J.D. Sr. Strategic Advisor & Director
Dr. Eric E. Swayze Ph.D. Exec. VP of Research
Mr. Joel Edwards VP of Corp. Operations
Mr. Darren Gonzales Chief Accounting Officer & Sr. VP
Dr. C. Frank Bennett Exec. VP & Chief Scientific Officer

Exchange: NASDAQ

Country: US : United States of America

Currency: US Dollar ($)

Forward PE: 90.9091
Trailing PE: 544.7143
Price-to-Book MRQ: 9.1536
Price-to-Sales TTM: 6.1754
IPO Date: 1991-05-17
Fiscal Year End: December
Full Time Employees: 660
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