Corbus Pharmaceuticals Holding(337)

Description: Corbus Pharmaceuticals Holdings, Inc., a biopharmaceutical company, focuses on the development of immune modulators for immuno-oncology and fibrosis diseases. It develops lenabasum, an oral molecule that selectively activates cannabinoid receptor type 2 (CB2), which is in Phase II clinical trial to treat systemic lupus erythematosus; CRB-601, an anti-integrin monoclonal antibody (mAb) for the treatment of cancer and fibrosis that inhibits the activation of transforming growth factor ß (TGFß); and CRB-602, an anti-avß6/avß8 mAb that blocks the activation of TGFß for the treatment of fibrotic diseases. The company is also developing cannabinoid receptor type 1 inverse agonist program for the treatment of metabolic disorders, such as obesity, diabetic nephropathy, diabetic retinopathy, and nonalcoholic steatohepatitis; fibrotic diseases, including lung, cardiac, renal disease, and liver fibrosis; and other diseases comprising ascites, cognitive defects, Prader-Willi syndrome, and smoking cessation. It has a licensing agreement with Jenrin Discovery, LLC to develop and commercialize the licensed products, including the Jenrin library of approximately 600 compounds, and multiple issued and pending patent filings. The company was incorporated in 2009 and is based in Norwood, Massachusetts.

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Keywords: Cancer Biopharmaceutical Disease Treatment Of Cancer Hepatitis Obesity Kidney Disease Diabetic Retinopathy Fibrosis Metabolic Disorders Steatohepatitis Non Alcoholic Fatty Liver Disease Systemic Lupus Erythematosus Renal Disease Diabetic Nephropathy Carboxylic Acids Liver Fibrosis Fibrotic Disease Prader Willi Syndrome Ajulemic Acid Fibrosis Diseases Treatment Of Fibrotic Diseases Treatment Of Metabolic Disorders

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Home Page: www.corbuspharma.com

500 River Ridge Drive
Norwood, MA 02062
United States
Phone: 617 963 0100

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Officers

Exchange: F

Country: DE : Germany

Currency: Euro (€)