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Crest Nicholson Holdings plc(CRTHF)

Description: CARsgen Therapeutics Holdings Limited, an investment holding company, engages in discovering, developing, and commercializing chimeric antigen receptor T (CAR-T) cell therapies for the treatment of hematological malignancies and solid tumors in China and the United States. The company is developing autologous CAR-T product candidates, including CT053, which targets B-cell maturation antigen that is in pivotal Phase II/III trial for the treatment of relapsed/refractory multiple myeloma; CT041, which targets Claudin 18.2, is in Phase II/III clinical trial for gastric/gastroesophageal junction cancer and pancreatic cancer, as well as in Phase I clinical trial for gastric or pancreatic cancer; CT011, which is in Phase I clinical trial for patients with Glypican-3 positive IIIa hepatocellular carcinoma (HCC); and CT071, that is in Phase I clinical trial which targets G protein-coupled receptor class C group 5 member D for the treatment of R/R MM and relapsed/refractory primary plasma cell leukemia (R/R pPCL). It is also developing CT0180 and CT0181, which targets Glypican-3 that is in Phase I clinical trial for the treatment of hepatocellular carcinoma. In addition, the company is developing CT0590, which targets B-cell maturation antigen that is in Phase I clinical trial for the treatment of relapsed/refractory multiple myeloma; CT048, which targets Claudin 18.2 that is in Phase I clinical trial for the treatment of gastric/gastroesophageal junction and pancreatic cancer; KJC2113 that targets mesothelin, as well as KJ-C2114 that are in pre-clinical stage for the treatment of solid tumors; and KJ-C2320 for acute myeloid leukemia that is in pre-clinical stage. Further, it develops AB011, which is in Phase I clinical trial for the treatment of gastric/pancreatic cancer. The company has a license agreement with HK Inno.N Corporation to develop and commercialize CT032 for the treatment of CD19. The company was founded in 2014 and is headquartered in Shanghai, China.


Keywords: Solid Tumors Cancer Immunotherapy Acute Myeloid Leukemia Pancreatic Cancer Hepatocellular Carcinoma Orphan Drug Hematological Malignancies Relapsed/Refractory Multiple Myeloma Seagen Ab011 Ct011 Ct041

Home Page: www.carsgen.com

No. 466 Yindu Road
Shanghai,
China
Phone: 86 21 6450 1828


Officers

Name Title
Dr. Zonghai Li M.D., Ph.D. Co-Founder, CEO, Chief Scientific Officer & Chairman of the Board
Dr. Huamao Wang Ph.D. Co-Founder, COO & Executive Director
Dr. Hua Jiang Executive Director
Dr. Hong Ma Senior Vice President of Clinical Development
Dr. Leigh Hsu Senior Vice President of Business Development
Dr. Raffaele Baffa M.D., Ph.D. Chief Medical Officer
Dr. Sylvie Peltier Senior Vice President of Global Regulatory Affairs
Mr. Wing Yat Lui Company Secretary

Exchange: PINK

Country: US : United States of America

Currency: US Dollar ($)

Forward PE: 0
Trailing PE: 0
Price-to-Book MRQ: 1.9824
Price-to-Sales TTM: 64.6285
IPO Date:
Fiscal Year End: October
Full Time Employees: 477
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